public:rem4:rem4-18:design_of_comparative_experiments_ii

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#### Overview

True Experimental Designs: Procedure |

Some Statistical Methods for Experimental Designs: What to Use When |

t-test |

Using Models to Validate and Measure: The Model Human Processor |

Next Project: Write Contributions, Results, Conclusion |

#### Concepts

Independent variables | We select their values - the values are known when we start an experiment. Any independent variable must have at least 2 levels (values), so its effect can be evaluated. |

Levels | Relating to an independent variable: The number of levels of an independent variable is equal to the number of variations of that variable used in an experiment. |

Dependent variables | Values are measured during and/or after the experiment. |

Sample: subject selection from a “population” A representative subset, drawn from a population, of the phenomenon we are studying. | Examples: a. Siggi, Maggi and Biggi representing human males. b. 10 lakes representing all freshwater on the Earth's surface. c. rust on bottom of doors representing the overall state of an automobile. A sample should be randomly chosen to (1) minimize spurious correlations and thus (2) maximize the generalizability of the results of measuring only a small subset of the phenomenon. |

Spurious correlation | “false” correlation - correlation that implies a connection between things measured, where there is no causal relationship between them, in and of themselves. |

Between-subjects design | If our control group in an experiment contains different instances than the experimental group. |

Within-subjects design | When the instances in our experimental group serve as their own control group. |

Internal validity | How likely is it that the independent variables caused the dependent variables? |

External validity | How likely is it that the results generalize to other instances of the phenomenon under study? |

#### True Experimental Designs: Procedure

Identify the phenomenon to study | Characterize it in ways that make it easy to study. |

Ask the right question(s) | “A question well asked is a question half-answered.” |

Identify variables that matter | Independent and dependent. |

Choose experimental design | Based on the nature of the experiement, but some flexibility with regards to how detailed/reliable/etc. the results should be. |

Design the setup | Identify all factors that could potentially confound your results. |

Execute the experiment | Double-blind procedure: The experimenter does not know which group a subject belongs to and/or which level of an independent variable is being tested. |

Collect the data | Use tables, graphs, as appropriate - very important to choose right presentation method. |

Apply statistical tests | Make sure you select the right statistical test based on your design and your knowledge of the relationship between your sample and your population, and the distribution and means of the population that the sample is drawn from. |

Draw conclusions from statistical tests | Use inference, based on probabilities, statistical significance. |

Write up the report |

#### Some Statistical Methods for Experimental Designs: What to Use When

Selecting between hypotheses | Statistical tests help you figure out whether the difference (in means and distribution) observed in a dependent variable (as measured between two samples) is large enough to indicate a non-coincidence. To make this judgement, the “natural” variation in each group is used as a “baseline”. Significance level is a measure that tells you how non-coincidental you want your measure to be, to be considered as “significant”. p<0.05 and p<0.01 are most common (less than 5%, 1% probability of the result being random). |

What you study | What you use |

Two factors varying along a continuum | Correlation/regression measures |

Two factors, where independent variable has (or can have) a few discrete values | t-test |

One dependent variable, multiple independent variables, each with two or more levels | ANOVA - Analysis of variance |

Many dependent variables, many independent variables | MANOVA (multiple analysis of variance) |

#### t-test

A fairly robust test for simple comparison experiments | Assumptions about population means and distributions can be violated without too much trouble. |

Sample size | Good for small sample sizes |

Paired t-test | Used for within-subjects designs |

Standard t-test | For between-subjects designs |

#### Using Models to Validate and Measure - a.k.a. Simulation

What simulation is | A simplified model of subject under study - that is, a simplification not of the key causal factors in the phenomenon, which must remain in our model for it to be useful, but rather a reduction (sometimes a radical one) of the “extra stuff that really doesn't matter”. |

What it does | Simplifies! Makes it easier to (A) set up testing conditions, (B) control independent variables, (C) make changes to the independent variables,(D) measure the results. |

When to use | When the complexity of that which is to be modeled/understood becomes so great that mathematical models are intractable and hypothesis falsification would take decades, centuries or millennia, or is simply out of the question (as in e.g. astrophysics). |

Kinds of simulation methodologies | Continuous time and state: E.g. differential equations. Discrete time/state: E.g. automata. |

Relation between scientific theories and simulations | To build a simulation we need a theory that tells us how things relate to each other. |

Procedure | Pick methodology. Decide which kinds of questions to answer. Model major states/transitions or input/output/functional properties of system. Run simulations with variations in independent variables. Note outcome. Fix model. Repeat. |

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